Expression Studio has many great tools to design web pages, html,silverlight or just shapes,pictures etc.AlsoExpression Design, one of the family member, has a very important feature that can ease our web desing in its first stages.We can design our page with its html not just its pictures.So let' s start:
1.First create a new document.
Here size of the document is important because it is related with our web page's resolution we want
2.Draw the header part.

To draw this rectangle use rectangle tool in toolbox.
With this rectangle tool draw other parts: left navigation bar, footer and menu:
After that now with slice tool draw slices for parts (footer, header etc.)
Just make rectangles around page parts.After finishing ctrl+e for exporting:

Here adjust setting of slices.Give logical name them because these names will be corresponding <div> names in html and will affect our all design.In container options select Html & Images:
Now your html and pictures are ready in the directory you selected.